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Hong Kong – A crucial player in genomic integrity maintenance, DNA Polymerase Theta (Polθ) provides a potential synthetic lethal relationship in BRCA-deficient tumors, which are particularly prevalent in certain tumor types including triple-negative breast cancers (TNBC) and ovarian cancers. In fact, BRCA-deficient tumors account for 11-16% of TNBC cases, and...
Dallas, Texas – Despite causing serious symptoms and having available treatments, Lambert-Eaton myasthenic syndrome (LEMS) may be frequently missed in people with lung cancer, a new study suggests. While previous studies have suggested that about 3% to 6% of people with small cell lung cancer (SCLC) develop LEMS, this claims analysis...
EL PASO, Texas – Researchers at The University of Texas at El Paso have identified a novel pharmaceutical compound that successfully kills leukemia and lymphoma cancer cells, potentially paving the way for new forms of therapy. Renato Aguilera, Ph.D., a professor in the Department of Biological Sciences, is the principal...