SHANGHAI, China — Dizal Pharmaceutical today announced that the results of a phase 2 pivotal study of sunvozertinib for the treatment of platinum-pretreated non-small-cell lung cancer (NSCLC) patients with EGFR exon 20 insertion mutations (exon20ins) (WU-KONG6) were published in the peer-reviewed journal The Lancet Respiratory Medicine. The publication of these...
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Heidelberg, Germany – Medulloblastoma is one of the most common malignant tumors of the central nervous system (CNS) in children and adolescents. It develops in the area of the cerebellum, which is responsible for movement coordination, among other things. Medulloblastomas enlarge rapidly, often grow into surrounding tissue and can also...
Umeå, Sweden – A pioneering study at Umeå University, Sweden, has unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumour known as glioblastoma. Having identified the factors that glioblastoma uses to respond to neurons by growing and spreading, this discovery paves the way...
MOUNTAIN VIEW, Calif. & BOSTON, Mass. — DNAnexus, Inc., the provider of the Precision Health Data Cloud, and TMA Precision Health, a global health platform for rare diseases, today announced a collaboration to advance basic and translational research for patients who have a rare disease. As part of the agreement,...
Venice, Italy – New research being presented at the European Congress on Obesity (ECO) in Venice, Italy (12-15 May), and published in the International Journal of Obesity, could help explain why type 2 diabetes is more common in men than in women. “Previous studies have shown that men develop type...
CHAPEL HILL, NC — Eating food and absorbing its nutrients is an everyday occurrence, but this normal activity can look different for someone who suffers from inflammatory bowel disease. IBD, which includes Crohn’s disease and ulcerative colitis, can cause chronic inflammation of the digestive tract – which for many reasons...
Hoboken, New Jersey – New research indicates that individuals with persistent and worsening metabolic syndrome—which encompasses conditions such as high blood pressure, elevated blood sugar, excess abdominal fat, and abnormal cholesterol—face an elevated risk of developing various types of cancer. The findings are published by Wiley online in CANCER, a...
Mainz, Germany – The protein TDP-43 is present in all cells of our body and important for their biochemical processes. However, this protein can aggregate into large clumps in the brain, which can cause degenerative diseases such as Alzheimer’s and other dementias. How exactly this happens and how these protein...
MIAMI, FLORIDA – Patients with multiple myeloma are living longer, healthier lives thanks to a host of new immunotherapies and targeted drugs. But there is still no cure for the disease, the second most common blood cancer. Physician-scientists at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller...
Ann Arbor, Mich. – Over the last decade, research at Michigan Medicine has shown how exposure to toxins in the environment, such as pesticides and carcinogenic PCBs, affect the risk of developing and dying from amyotrophic lateral sclerosis. Now, investigators have developed an environmental risk score that assesses a person’s risk...