CHATHAM, N.J. — Tonix Pharmaceuticals Holding Corp. (Nasdaq: TNXP) (Tonix or the Company), a fully-integrated biopharmaceutical company with marketed products and a pipeline of development candidates, today announced that Seth Lederman, M.D., Chief Executive Officer of Tonix Pharmaceuticals, will present at the 2025 BIO-Europe Spring Convention being held March 17-19,...
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BERKELEY HEIGHTS, N.J. — Tonix Pharmaceuticals Holding Corp. (Nasdaq: TNXP) (“Tonix” or the “Company”), a fully-integrated, commercial stage biotechnology company, today announced the publication of a paper, “Steady-State Pharmacokinetic Properties of TNX-102 SL, a Sublingual Tablet Formulation of Cyclobenzaprine Hydrochloride (HCl), With Daily Dosing in Healthy Volunteers: A Randomized, Open-Label...
RESEARCH TRIANGLE PARK, N.C. – Worldwide Clinical Trials, Inc., (Worldwide) the industry’s leading global, midsized, full-service contract research organization (CRO), announced researchers Anna Gres, Ph.D. and Matthew Confeld, Ph.D., Pharm.D., have been selected for the esteemed Michael F. Murphy Clinical Research Methodology Fellowship Program. Established in 2017, the competitive two-year program...
Ionis completed a Phase 2 clinical study evaluating cimdelirsen (IONIS-GHR-LRx) as an addon therapy in patients with uncontrolled acromegaly despite stable therapy with long-acting somatostatin receptor ligands (SRL). Based on the results of this Phase 2 study and a preliminary analysis of the ongoing open-label study, proof of mechanism was...
Compared with chemotherapy conditioning, total body irradiation (TBI) may lead to better outcomes prior to allogeneic hematopoietic stem cell transplantation (HSCT) in pediatric patients with acute lymphoblastic leukemia (ALL), according to research in the Journal of Clinical Oncology. Patients with ALL commonly receive TBI and etoposide before undergoing HSCT; however there...
At night, after Tammy Hruskach tucks her boys in bed, she prays a mother’s prayer for constant protection and guidance — first for Logan, 9; and then for her 7-year-old, Austin. “And God,” she always adds as she brushes the bangs off Austin’s forehead, her hand lingering in one last...
BOSTON, Mass. — Compass Therapeutics, Inc. (Nasdaq: CMPX), a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics, today announced that it met the key secondary endpoint of PFS and showed additional compelling results in the randomized COMPANION-002 study, which evaluated tovecimig plus paclitaxel versus paclitaxel alone in patients with unresectable...
BOSTON, Mass. — Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading. Multiple therapeutic cancer vaccines are being studied in clinical trials, but despite their promise, they are not routinely...
IBEC researchers led by Javier Ramón and Juan M. Fernández develop the first three-dimensional model for myotonic dystrophy, a rare disease that currently has no cure. The model combines patient cells and bioengineering techniques and represents a major advance over the use of animals and cell cultures. This new model...
Barcelona, Spain – Alterations in the TP53 gene represent an intrinsic biomarker of very poor outcomes in pediatric and young adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL) treated with the anti-CD19 CAR-T therapy tisagenlecleucel (tisa-cel). This was discovered by a group of Spanish researchers, who recently...