Osaka, Japan – Treating rare diseases can be complicated at the best of times, and it gets even more complicated when different patients with the same disease exhibit different symptoms. Now, researchers from Japan have reported a cellular signature that might explain why some patients with autoimmune disease are stable...
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Ottawa, Canada – A University of Ottawa neuroscientist’s personal battle with cancer has inspired new research geared toward tailoring radiation treatment to reduce damage to the brain. Cancer treatments – including radiation therapy – can have debilitating effects on patients, weakening the immune system and leading to memory and cognitive...
Ottawa, Canada – Glioblastoma is the most common – and the most malignant – primary brain tumour in adults. It’s aggressive and incurable. Even with treatment including surgical removal and chemotherapy, the median survival for patients is just 18 months. Now, innovative new research led by Dr. Arezu Jahani-Asl, Canada Research Chair in Neurobiology of...
Ottawa, Canada – A team from the University of Ottawa’s Faculty of Medicine has completed an exciting new study that reveals the inner workings of gene mutations that result in an ultra-rare syndrome with fewer than 100 reported cases since its first description in the early 1960s. The hard-won research...
Philadelphia, PA – Researchers from the University of Pennsylvania, Perelman School of Medicine, Gene Therapy Program, and Moderna, have shown that repeated administration of lipid nanoparticle-encapsulated mRNA therapy significantly extended survival and reduced serum leucine levels in a mouse model of maple syrup urine disease (MSUD). Click here to read...
PHILADELPHIA, PA – When cells in the human body divide, they must first make accurate copies of their DNA. The DNA replication exercise is one of the most important processes in all living organisms and is fraught with risks of mutation, which can lead to cell death or cancer. Now,...
Pittsburgh, PA. – Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media. The findings, published recently...
PITTSBURGH, PA – A self-destructing vaccine administered intravenously provides additional safety and protection against tuberculosis (TB) in macaque monkeys, suggests new University of Pittsburgh research published today in Nature Microbiology. The in-built safety mechanisms circumvent the possibility of an accidental self-infection with weakened mycobacteria, offering a safe and effective way...
Brisbane, Australia – University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited. Dr Anne Hahn and Associate Professor Steven Zuryn from UQ’s Queensland Brain Institute said the findings could provide a promising therapeutic avenue to stop the onset of heritable and age-related...
Brisbane, Australia – University of Queensland researchers have identified an opportunity to reduce infections in people living with cystic fibrosis. Professor Matt Sweet, Dr Kaustav Das Gupta and Dr James Curson from UQ’s Institute for Molecular Bioscience have discovered a fault in the bacteria-killing function of immune cells in people...