JUPITER, FL. – Current tests to identify specific strains of infectious prions, which cause a range of transmissible diseases (such as mad cow) in animals and humans, can take anywhere from six months to a year to yield results – a time-lag that may put human populations at risk. Now,...
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LA JOLLA, CA—Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane’s challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed proteins that can efficiently reach these “intramembrane” targets. In their study, published in Nature Chemical Biology, the researchers used...
LA JOLLA, CA — Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously difficult to block with drugs—but that may soon change....
JERSEY CITY, N.J. — SCYNEXIS, Inc., (NASDAQ: SCYX), a biotechnology company pioneering innovative medicines to overcome and prevent difficult-to-treat and drug-resistant infections, today announced the presentation of preclinical efficacy data on its second generation fungerp candidate SCY-247. Dr. Ashraf Ibrahim, PhD, FAAM, FECCM, Professor of Medicine in the Division of...
DENVER, CO — SeaStar Medical Holding Corporation, a medical device company developing proprietary solutions to reduce the consequences of hyperinflammation on vital organs, announces enrollment of 12 subjects in the NEUTRALIZE-AKI pivotal clinical trial evaluating the safety and efficacy of its patented, first-in-class, cell-directed Selective Cytopheretic Device (SCD) extracorporeal therapy...
LISSES, France – Sebia, a leading provider of clinical protein electrophoresis equipment and reagents for diabetes and oncology detection, today announced the acquisition of specialty diagnostic leader ORGENTEC Diagnostika from Water Street Healthcare Partners, a strategic investor focused exclusively on healthcare, for an undisclosed amount. The transaction is expected to close in the next quarter. The...
When their second child was only a couple of months old, the Liews noticed that he didn’t seem to be growing and that his stomach was bulging. At first, they thought nothing of it but when little Liew Yong Tai was a year old, he was diagnosed with beta thalassaemia...
PHILADELPHIA, PA – The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine, researchers from the Perelman School of Medicine at the University of Pennsylvania reported today in Nature...
KING OF PRUSSIA, Pa. — SEED Therapeutics Inc., a biotechnology company pioneering the discovery of molecular glues for targeted protein degradation (TPD) using its proprietary RITE3™ platform, today announced that the U.S. Food and Drug Administration (FDA) has granted Rare Pediatric Disease and Orphan Drug designations to SEED’s ST-01156 molecular...
NEW YORK – Seelos Therapeutics, Inc. (Nasdaq: SEEL), a clinical-stage biopharmaceutical company focused on the development of therapies for central nervous system disorders and rare diseases, announced it has entered into an exclusive license agreement (License Agreement), whereby it acquired a worldwide license (excluding China, Taiwan, Macau and Hong Kong)...