Evanston, Illinois – Scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington’s disease, an incurable, debilitating illness that causes nerve cells to break down in the brain. Patients with Huntington’s disease have a genetic mutation that triggers proteins to misfold and clump together...
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MEMPHIS, Tenn. – St. Jude Children’s Research Hospital scientists improved chimeric antigen receptor (CAR) T–cell immunotherapy for acute myeloid leukemia (AML), demonstrating better efficacy in the lab. To overcome common problems with CAR T cells, the researchers created an additional means for the therapy to find and eliminate cancer cells,...
Solna, Sweden – Using advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop. The new results are presented in the journal Cell by researchers from Karolinska Institutet and Stockholm University. Over 1,8 million people worldwide are diagnosed with multiple sclerosis,...
CAMBRIDGE, MA — Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways — some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA. Until now, there has been no way to...
Milwaukee, Wis. – There is nothing magic about the recent increase in interest around the study of psychedelic drugs as potential treatments for patients suffering from a myriad of mental health conditions. “The excitement follows the science,” says John McCorvy, PhD, assistant professor of cell biology, neurobiology and anatomy...
Adelaide, Australia – For decades, hormonal treatment of breast cancer has been going in one direction – blocking estrogen. Now a global study involving researchers at the University of Adelaide has discovered there may be another, less toxic way to defeat the most common form of breast cancer. The study...
Copenhagen, Denmark – It turns out that a particular gene has a great influence on longevity, a new study from the University of Copenhagen concludes. This may pave the way for new treatment. Sleep, fasting, exercise, green porridge, black coffee, a healthy social life … There is an abundance of...
Ann Arbor, Mich. – Blood clots and pregnancy loss are commonly recognized features of antiphospholipid syndrome, but thrombocytopenia is the third most prevalent symptom, impacting up to half of antiphospholipid syndrome patients. Thrombocytopenia is characterized by lower than normal platelets in the blood. Platelets are small cell fragments that play...
San Francisco, Calif. – Immunotherapies using engineered T cells have ushered in a new era in cancer treatment, but they have their limits. They may cause side effects or stop working, and they do not work at all against 90% of cancers. Now, scientists at UC San Francisco and Northwestern...
San Francisco, Calif. – Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma – and a potential new target for treatment. Neuroblastoma accounts for 15% of all pediatric cancer deaths and is the most common source of childhood tumors outside of brain cancer. The disease develops...