Barcelona, Spain – Researchers have discovered key mutations in certain cancer cells that make them resistant to WRN inhibitors, a new class of anti-cancer drugs. The yet-to-be-published findings are presented on Friday at the 36th EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain. Werner helicase (WRN)...
Latest News
Philadelphia, PA – Advancements in the care of premature babies are leading to improved survival rates. However, the incidence of neonatal diseases with life-long consequences such as bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) is increasing. A novel study has implicated granulocyte colony-stimulating factor (G-CSF) in both BPD and...
DURHAM, N.C. – The brain’s neurons tend to get most of the scientific attention, but a set of cells around them called astrocytes – literally, star-shaped cells – are increasingly being viewed as crucial players in guiding a brain to become properly organized. Specifically, astrocytes, which form about half the...
BUFFALO, NY – A new research paper was published on the cover of Aging Volume 16, Issue 3, entitled, “GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects.” GV1001, which mimics the activity of human telomerase reverse transcriptase, protects neural cells from amyloid beta (Aβ) toxicity...
HOUSTON, Texas – Houston Methodist researchers identified a troublesome subset of T-cells in transplant recipients that may be a more effective therapeutic target for preventing transplant rejection in patients. Each day, 17 people die waiting for organ transplants, but getting a new organ doesn’t guarantee survival. Despite immunosuppressive medications, rejection...
Singapore – Dengue is often a mild disease. However, a minority of infections may progress to severe dengue, which could be life-threatening for patients that do not have access to close monitoring and specialised medical care. While dengue infection is usually diagnosed based on a clinical assessment by a doctor...
Osaka, Japan – Your skin becomes red and spots filled with pus appear, so you visit a dermatologist. When these symptoms spread to the skin throughout the body, it is difficult for the physician to distinguish whether it is generalized pustular psoriasis (GPP) or acute generalized exanthematous pustulosis (AGEP), as...
Osaka, Japan – Antisense oligonucleotides (ASOs) are next-generation drugs that can treat disease by blocking the transfer of harmful messages from our genes. In people with cancer, ASOs have the potential to block messages that encourage the growth and spread of the tumor. However, ASOs aren’t used for treating cancer...
Osaka, Japan – More than bad breath, there is growing evidence that ongoing inflammation in the mouth, like with gum disease, is associated with serious diseases such as Alzheimer’s disease or type 2 diabetes. Now, researchers from Osaka University have identified an easy way to fight bacteria that might cause...
State College, PA – A newly developed “GPS nanoparticle” injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State. They tested their approach in human cell lines and in mice to effectively...