DAVIS, Calif. – Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed. Severe pancreatic cancer is associated with metastasis, and it is this spread of secondary tumors that usually causes death, but little is...
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Washington, D.C – Preeclampsia is a life-threatening pregnancy complication marked by persistent high blood pressure that is even more serious when it occurs early in the first trimester. The exact cause of early-onset preeclampsia is unknown, and it is difficult to predict, prevent and diagnose. Now, in ACS’ Journal of...
PHILADELPHIA, PA – An international study group led by researchers of Children’s Hospital of Philadelphia (CHOP) have identified how three novel genes cause neurodevelopmental disorders. Researchers now have a better sense of the genes’ roles in human brain development and function and their ability to serve as potential therapeutic targets...
Atlanta, Georgia – For over three decades, a highly accurate early diagnostic test for ovarian cancer has eluded physicians. Now, scientists in the Georgia Tech Integrated Cancer Research Center (ICRC) have combined machine learning with information on blood metabolites to develop a new test able to detect ovarian cancer with...
Cambridge, UK – The saying “Knowing is half the battle” is never more true than when discussing early treatment of disease. Muscular dystrophy is one such disease where patients can benefit from early treatment. Now, new research is moving doctors and scientists closer to disease diagnosis in advance of patient...
CAMBRIDGE, England – Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body. They have identified the sequence within the mRNA that causes this to occur and found a way to prevent ‘off-target’ immune responses to enable the...
BALTIMORE, MD — Researchers at Kennedy Krieger Institute and Boston Children’s Hospital have discovered a new way to decrease early seizure likelihood and improve neurologic outcomes among infants with Sturge-Weber Syndrome (SWS). This collaboration, funded by National Institutes of Health, is the first multi-center study of its kind focused on...
ANN ARBOR, Michigan — To understand why some cancers successfully circumvent the immune system to grow unchecked, researchers turned to pregnancy. “In pregnancy, the immune system does not reject the growing fetus, so we know there must be mechanisms active in the placenta. In cancer, it’s the same thing: the...
Houston, Texas – An international team of researchers has provided a genetic diagnosis for 30 individuals whose condition was undiagnosed for years despite extensive clinical or genetic testing. The study, conducted by researchers at Baylor College of Medicine, National University of Singapore and collaborating institutions worldwide, appeared in Genetics in...
Sidney, Australia – Innovative study of DNA’s hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer. DNA is well-known for its double helix shape. But the human genome also contains more than 50,000 unusual ‘knot’-like DNA structures called i-motifs, researchers at the Garvan Institute...