Hong Kong – A crucial player in genomic integrity maintenance, DNA Polymerase Theta (Polθ) provides a potential synthetic lethal relationship in BRCA-deficient tumors, which are particularly prevalent in certain tumor types including triple-negative breast cancers (TNBC) and ovarian cancers. In fact, BRCA-deficient tumors account for 11-16% of TNBC cases, and...
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SAN ANTONIO, TX – Research led by in part by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) finds that the most common cerebral small-vessel disease feature seen in brain magnetic resonance imaging is a primary vascular factor associated with dementia risk. Results of...
SALT LAKE CITY, Utah — While many babies are born without issues on a daily basis, there are quite a few who are born early and with some complications. Those babies end up in the Neonatal Intensive Care Unit (NICU), which is where Dr. Sabrina Malone Jenkins works. The Neonatologist...
EL PASO, Texas – Researchers at The University of Texas at El Paso have identified a novel pharmaceutical compound that successfully kills leukemia and lymphoma cancer cells, potentially paving the way for new forms of therapy. Renato Aguilera, Ph.D., a professor in the Department of Biological Sciences, is the principal...
EL PASO, Texas — Researchers at The University of Texas at El Paso are developing a new therapeutic approach that uses nanoparticles for the treatment of skin and pulmonary fibrosis, conditions that can result in severe damage to the body’s tissues. Md Nurunnabi, Ph.D., is an associate professor in UTEP’s...
Houston, TX – A medication that appeared to stabilize the function and shape of red blood cells in an earlier study for patients with sickle cell disease is now part of a Phase III clinical trial that is open for enrollment at UTHealth Houston. The trial, led locally by Modupe Idowu,...
Houston, Texas – A four-year, $3.4 million grant to investigate molecular mechanisms and therapeutic treatments for acute respiratory distress syndrome (ARDS) has been awarded to UTHealth Houston researchers by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health. The study led by principal investigators Holger Eltzschig,...
HOUSTON, TX – The body’s immune response to Epstein-Barr virus (EBV) may play a role in causing damage in people with multiple sclerosis, according to a new study led by UTHealth Houston. EBV infection has long been associated with multiple sclerosis, but how the infection might contribute to multiple sclerosis...
Munich, Germany – A team from the Technical University of Munich (TUM) has decoded the factor that makes T cell lymphomas grow comparatively rapidly: A missing “emergency shut-off switch” results in the lymphomas processing particularly large amounts of sugar and triggers other processes as well. Medications for other types of...
San Antonio — Two of the world’s leading Alzheimer’s researchers have co-edited a book critically synthesizing the major new developments in the diagnosis and treatment of Alzheimer’s disease. Building upon a 2007 Alzheimer’s disease conference held in Chile, George Perry, dean of the College of Sciences at The University of...