LA JOLLA, CA — Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify proteins—and their specific parts—that future drugs should target. But when used on...
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Laurel Hollow, NY – Cancer cells have voracious appetites. And there are certain nutrients they can’t live without. Scientists have long hoped they might stop tumors in their tracks by cutting off an essential part of cancer cells’ diet. But these cells are crafty and often find a new way...
—Largest Global Clinical Trial Ever Conducted in Bronchiectasis Demonstrates Statistically Significant and Clinically Meaningful Reduction in Frequency of Pulmonary Exacerbations Versus Placebo— —Brensocatib 25 mg is the First Investigational Therapy for Bronchiectasis to Show a Statistically Significant Reduction in the Rate of Lung Function Decline— —Brensocatib is Currently Under Priority...
SILVER SPRING, Md. & RESEARCH TRIANGLE PARK, N.C. — United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced that the New England Journal of Medicine has published the full results of its TETON-1 study, as well as combined analyses of its TETON-1 and TETON-2 studies, evaluating the use of nebulized Tyvaso for the treatment of IPF....
Ridgefield, Conn. and Ingelheim, Germany — Boehringer Ingelheim today announced that The New England Journal of Medicine (NEJM) published results from the Phase 1b Beamion LUNG-1 trial of HERNEXEOS® (zongertinib tablets) in treatment-naïve patients with advanced non-small cell lung cancer (NSCLC) who have HER2 activating mutations in the tyrosine kinase domain (TKD). The data...
Atlanta, GA – Myasthenia gravis (MG) is a chronic autoimmune disorder in which antibodies block communication between nerves and muscle, resulting in weakness of the skeletal muscles. It can cause double vision, difficulty swallowing, and, occasionally, serious breathing difficulties, among other symptoms. Many autoimmune diseases such as MG, as well as...
COLUMBUS, Ohio – A new study in mice hints at the promise of an eventual alternative treatment option for the “wet” version of age-related macular degeneration (AMD). Researchers determined in mice that an enzyme related to cell growth and division is a culprit in the blood vessel invasion in the...
Scientists have discovered in more detail than ever before how the human body’s immune system reacts to malaria and sickle cell disease. The researchers from the universities of Aberdeen, Edinburgh, Exeter and Imperial College, London have published their findings in Nature Communications. Every year there are ~200 million cases of...
Baltimore, Maryland – A so-called pathological protein long associated with Parkinson’s disease has been found in a new study to trigger cells to increase protein synthesis, an event that eventually kills the subset of brain cells that die off in this neurodegenerative condition. Researchers from the Johns Hopkins University School...
PLYMOUTH MEETING, PA — New research in the April 2024 issue of JNCCN—Journal of the National Comprehensive Cancer Network showcases the feasibility of improving early detection and prevention for pancreatic cancer. Global incidences of pancreatic cancer have risen dramatically in recent years, but the overall survival rate is currently only...