BASEL, Switzerland – The US Food and Drug Administration (FDA) has approved Ilaris® (canakinumab) for the treatment of children and adults with cryopyrin-associated periodic syndrome (CAPS), which includes a number of rare but life-long auto-inflammatory disorders with debilitating symptoms and limited treatment options[1],[2],[3],[4]. The FDA granted priority review to Ilaris...
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Houston, TX – New biomarkers with improved diagnostic performance for early detection of lupus nephritis have been discovered in the University of Houston lab of Chandra Mohan, a pioneer in lupus research. Early identification of renal involvement in lupus and prompt treatment are essential in reducing the pain, suffering and...
Baltimore, Maryland – By 2040, experts estimate that nearly 400,000 people worldwide will be living with amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig’s disease. This degenerative nervous system disease damages nerve cells responsible for controlling voluntary muscle movement, leading to progressive muscle weakness, loss of muscle mass and,...
Boston, Mass. – According to The National Institute on Deafness and Other Communication Disorders (NIDCD), Autism Spectrum Disorder, or ASD, can affect children’s language development and communication in a variety of ways. While some children with ASD may encounter difficulties communicating verbally, others exhibit impressive vocabularies and the ability to...
Sacramento, Calif. – A new brain-computer interface (BCI) developed at UC Davis Health translates brain signals into speech with up to 97% accuracy — the most accurate system of its kind. The researchers implanted sensors in the brain of a man with severely impaired speech due to amyotrophic lateral sclerosis...
New York, NY – Like many rare diseases, fibrolamellar hepatocellular carcinoma (FLC) mounts a ferocious attack against an unlucky few—in this case, children, adolescents, and young adults. Because its symptoms can vary from person to person, it’s often missed or misdiagnosed until it has metastasized and becomes lethal. Moreover, drug...
Cambridge, Mass. – Immunotherapy has revolutionized the treatment of many cancers, but brain tumors such as gliomas remain particularly difficult to treat, in part because they potently suppress immune responses. New findings from researchers at the Broad Institute of MIT and Harvard and the Dana-Farber Cancer Institute (DFCI) could help...
Stanford, Calif. – CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven’t experienced improvement with chemotherapy treatments. But if this CAR-T treatment fails, or the cancer returns yet...
CLEVELAND, Ohio — A groundbreaking study by researchers at Case Western Reserve University suggests a class of medications used to treat type 2 diabetes may also reduce the risk of colorectal cancer (CRC). The findings, published in the journal JAMA Oncology, support the need for clinical trials to determine whether...
CLEVELAND, Ohio — Researchers at Case Western Reserve University and University Hospitals have identified an enzyme that blocks insulin produced in the body—a discovery that could provide a new target to treat diabetes. Their study, published Dec. 5 in the journal Cell, focuses on nitric oxide, a compound that dilates...