Adelaide, Australia – For decades, hormonal treatment of breast cancer has been going in one direction – blocking estrogen. Now a global study involving researchers at the University of Adelaide has discovered there may be another, less toxic way to defeat the most common form of breast cancer. The study...
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Ann Arbor, Mich. – Blood clots and pregnancy loss are commonly recognized features of antiphospholipid syndrome, but thrombocytopenia is the third most prevalent symptom, impacting up to half of antiphospholipid syndrome patients. Thrombocytopenia is characterized by lower than normal platelets in the blood. Platelets are small cell fragments that play...
San Francisco, Calif. – Immunotherapies using engineered T cells have ushered in a new era in cancer treatment, but they have their limits. They may cause side effects or stop working, and they do not work at all against 90% of cancers. Now, scientists at UC San Francisco and Northwestern...
San Francisco, Calif. – Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma – and a potential new target for treatment. Neuroblastoma accounts for 15% of all pediatric cancer deaths and is the most common source of childhood tumors outside of brain cancer. The disease develops...
Seattle, Washington – Prostate cancer stands as a prevalent threat to men’s health, ranking second in cancer-related deaths in the United States. Each year, approximately 250,000 men in the U.S. receive a prostate cancer diagnosis. While most cases have low morbidity and mortality rates, a subset of cases demands aggressive...
Beijing, China – Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and Beijing Chaoyang Hospital have developed a new “pseudo cell” formulation based on self-healing microcapsule-loading exosomes to treat diverse vitreoretinal diseases. Vitreoretinal diseases include a wide spectrum of vision-threatening disorders, which may cause...
Plymouth, England – Scientists have developed a potentially transformative new technique that could aid in the discovery and development of new therapeutics for a number of globally prevalent autoimmune diseases. Conditions such as lupus, rheumatoid arthritis and inflammatory bowel disease (IBD) – as well as failures within transplanted cells –...
Your immune system plays an important function in your health — it protects you against viruses, bacteria, and other toxins that can cause disease. In autoinflammatory diseases, however, the immune system goes awry, causing unprovoked and dangerous inflammation. Now, researchers from the National Institute of Arthritis and Musculoskeletal and Skin...
São Paulo, Brazil – A protein that has been widely studied owing to its association with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) is also linked to medulloblastoma, a type of central nervous system cancer. Medulloblastoma is one of the most common and aggressive brain tumors in children, arising...
Sacramento, CA – Researchers at UC Davis Comprehensive Cancer Center have shown that inhibiting a specific protein using gene therapy can shrink hepatocellular carcinoma (HCC) in mice. Silencing the galectin 1 (Gal1) protein, which is often over-expressed in HCC, also improved the anti-cancer immune response and increased the number of killer T cells inside tumors....