The recombinant factor VIII (FVIII) therapy BAY 94-9027 demonstrated long-term safety and efficacy at reducing bleeds in pediatric patients with severe hemophilia A, according to results of a long-term analysis published in the journal Haemophilia. The analysis was the extension study of the phase 3 PROTECT VIII Kids trial (ClinicalTrials.gov Identifier: NCT01775618),...
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LA JOLLA, Calif. — Longboard Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company focused on developing novel, transformative medicines for neurological diseases, today announced that it will host a conference call to discuss topline data from the PACIFIC Study, a Phase 1b/2a clinical trial evaluating bexicaserin (LP352) in participants with a broad...
REDWOOD CITY, Calif. — Coherus Oncology, Inc. (NASDAQ: CHRS) today announced compelling six-year overall survival (OS) follow-up results from the Phase 3 JUPITER-02 trial evaluating LOQTORZI® (toripalimab-tpzi) plus chemotherapy in recurrent or metastatic nasopharyngeal carcinoma (RM-NPC). The findings reveal a striking and durable survival advantage that underscores the urgent clinical...
1. SYMPTOMS – “Mommy, I’m afraid. Tell me what to do.” The child’s mother looked up at her 8-year-old daughter. “It’s going to be O.K.,” she said. “Just go get some help.” The woman watched as her daughter left the public bathroom, where she now lay. She and her daughter...
Tokyo, Japan – Researchers from Tokyo Metropolitan University have studied pancreatic islet cell loss in people with no previous pancreatic problems. They identified key trends in the types of cells lost due to islet cell loss in different age groups and sexes, finding that ICL in the elderly population was...
Davis, California – New UC Davis research shows that men with an FMR1 premutation who experienced reduced executive function were at higher likelihood of developing fragile X-associated tremor/ataxia syndrome (FXTAS). FXTAS is a progressive genetic condition that causes movement issues and cognitive decline. These findings, published in the journal Movement...
Bologna, Italy – A new multi-center investigation has uncovered significant differences in the gut microbiome of children newly diagnosed with acute lymphoblastic leukemia (ALL), the most common childhood cancer. Using high-resolution shotgun metagenomic sequencing, researchers analyzed stool samples from 30 pediatric ALL patients across Italy and compared them with 176...
Portland, OR – New research from Oregon Health & Science University suggests that people with multiple sclerosis, or MS, could benefit from a low-fat diet to improve the fatigue that’s a debilitating, and often-underappreciated, symptom of the condition. The study, published online Wednesday in the Multiple Sclerosis Journal, is the latest in...
Saint Louis, Missouri – In Alzheimer’s disease and related dementias, cognitive decline is driven by the overaccumulation of a normal brain protein known as tau. Wherever tau builds up, nearby brain tissue starts to degenerate and die. Now, researchers at Washington University School of Medicine in St. Louis have found...
Charleston, SC – A new compound developed by researchers at MUSC Hollings Cancer Center shows promise in overcoming chemotherapy resistance in triple-negative breast cancer – and could potentially be applied to fibrotic conditions like liver fibrosis or pulmonary fibrosis. At the center of this work is preventing the protein lysyl...