Lausanne, Switzerland – Results from a preclinical study in mice, led by EPFL, and a collaborative clinical study in patients show that the type 2 immune response – associated with parasitic infection and thought to play a negative role in cancer immunity – is positively correlated with long-term cancer remission....
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Boston, MA – A significant survival improvement for adults with newly diagnosed BCR::ABL1-negative B-cell precursor acute lymphoblastic leukemia is published today by the New England Journal of Medicine. The practice-changing finding is from the randomized phase 3 study E1910 (NCT02003222), which evaluated blinatumomab immunotherapy in patients who were in remission...
London – The effectiveness of live zoster (shingles) vaccine is highest in the first year after vaccination and then wanes substantially. But it continues to provide some protection against shingles and its complications ten years after vaccination, even in patients with a weakened immune system, finds a study published by...
ST. PAUL, Minn. — One in four multiple sclerosis (MS) patients are declining to fill their prescriptions likely due to high out-of-pocket costs, according to new research conducted by pharmacy benefits manager Prime Therapeutics (Prime). The study found that patients with an out-of-pocket expense greater than $250 were seven times...
Salt Lake City, Utah – New research from Intermountain Health in Salt Lake City finds that genetic screening is effective in identifying patients who have a heart condition known as cardiomyopathy to improve their quality of life and reduce deaths. By undergoing genetic screening to identity those with the potentially-fatal...
London, UK – A new phase 1 study has demonstrated the safety and benefits of intravenous cardiosphere-derived cells (CDCs) in patients with various forms of pulmonary arterial hypertension (PAH). The study, published in The Lancet, found encouraging exploratory results and no clinical adverse events in the short or long term...
FRIENDSWOOD, Texas — Castle Biosciences, Inc., a company improving health through innovative tests that guide patient care, today announced the publication of a new study in The Journal of Clinical and Aesthetic Dermatology (JCAD) which found that using its DecisionDx-SCC test to guide ART decisions for patients with SCC could...
Cambridge, UK – Scientists have pinpointed genetic changes that can leave children born with little to no immune defence against infection. In a new study of 11 affected individuals, researchers from Newcastle University, the Wellcome Sanger Institute, the Great North Children’s Hospital, and their collaborators were able to link mutations...
BEIJING, China – Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease marked by the thickening and scarring of lung tissue with unclear etiology. Affecting around five million people worldwide, IPF causes severe respiratory problems and greatly diminishes the quality of life. Despite ongoing medical research, the exact...
Bristol, UK – While several trials have shown that substantial weight loss using diet and lifestyle can reverse type 2 diabetes, new research published in Diabetologia (the journal of the European Association of the Study of Diabetes) is among the first to show the subsequent impact of remission on cardiovascular...