Bethesda, Maryland – Researchers have shown that dangerous cysts, which form over time in polycystic kidney disease (PKD), can be prevented by a single normal copy of a defective gene. This means the potential exists that scientists could one day tailor a gene therapy to treat the disease. They also...
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PLYMOUTH MEETING, PA — The National Comprehensive Cancer Network® (NCCN®) is announcing several new updates to the cancer treatment practices listed in the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®). The evidence-based expert consensus recommendations are the most frequently updated guidelines for any area of medicine and are used...
Boston, Mass. – An important discovery from the NCI-MATCH precision medicine initiative is being published today in Clinical Cancer Research, a journal of the American Association for Cancer Research. Trastuzumab-pertuzumab, a drug combination approved by the US Food and Drug Administration (FDA) to treat patients with human epidermal growth factor...
CHICAGO — Most patients with Type 2 diabetes will end up needing to add a second-line medication after metformin — the go-to primary drug for glucose management — to control their blood sugar levels. But adherence to these second-line drugs can be hit or miss, reports a new Northwestern Medicine...
LINCOLN, Neb. (KOLN) -The annual Nebraska Football Road Race will return to an in-person format this summer with the family-friendly event set for Father’s Day on Sunday, June 20. The Nebraska Football Road Race presented by the Lincoln Track Club features the one-mile Fun Run set to begin at 8...
CORNWALL — Ryan Neiswender is as bright, perceptive and articulate as any 15-year-old could be. But for someone so intellectually aware, the soon-to-be Cedar Crest High School freshman appears to be profoundly oblivious to the fact that he’s been dealt a bad hand in life. That’s probably because when Neiswender...
BOSTON, Mass. – The NEJM Evidence has published interim data from the first part of Phase I/II CYPIDES trial evaluating the safety and efficacy of ODM-208 (or MK-5684), an investigational, oral CYP11A1 inhibitor, in heavily pretreated patients with metastatic castration-resistant prostate cancer (mCRPC). Prostate cancer continues to be regulated by...
SAN FRANCISCO – Nektar Therapeutics (Nasdaq: NKTR) today announced the publication of preclinical data in the Journal of Translational Autoimmunity describing NKTR-358, a first-in-class, composition of stable PEG conjugates of native IL-2 designed to selectively stimulate T regulatory (Treg) cell function. NKTR-358 is currently in development for the treatment of...
ORLANDO, Fla. — Injecting neuroblastoma tumors with Zika virus shrank or eliminated those tumors in studies with mice, suggesting that the virus could someday serve as an effective cancer therapy, according to a study led by Nemours Children’s Health researchers and published today in Cancer Research Communications, a journal of...
Jacksonville, Florida – Researchers from Nemours Children’s Health will present several studies at the American Society of Hematology (ASH) conference, Dec. 9-12 in San Diego. Nemours Children’s researchers will focus primarily on sickle cell disease (SCD), a group of inherited red blood disorders marked by defective hemoglobin that causes pain...