Sugar Land, Texas – Hepatic biliary adenofibroma (BAF) is a rare benign bile duct neoplasm that has garnered increasing attention due to its potential role as a precursor lesion for intrahepatic cholangiocarcinoma (iCCA). Although it shares histopathological features with other biliary tumors, BAF is distinct in its composition, consisting of...
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Sugar Land, Texas – Over the past two decades, there has been a significant increase in the incidence of primary liver cancer in the USA, with higher rates observed in men. Its burden increases with age and disproportionately affects men, with mortality rates three times higher in men than in...
FOSTER CITY, Calif. — Mirum Pharmaceuticals, Inc. (Nasdaq: MIRM) today announced that Hepatology published an analysis demonstrating a statistically significant improvement in six-year event-free and transplant-free survival in patients with Alagille syndrome (ALGS) treated with LIVMARLI® (maralixibat) oral solution when compared with a natural history control group (p<0.0001). The analysis...
Changchun, China – A new study published in the journal eGastroenterology provides an updated assessment of the diagnosis, pathophysiology, and treatment of hepatorenal syndrome-acute kidney injury (HRS-AKI). This severe and often fatal condition can occur in patients with cirrhosis. HRS-AKI is a functional and progressive kidney failure that is potentially...
MILFORD — Amanda Pitre, 30, lives with her parents and can only work part-time because she has an autoimmune disease that creates constant, burning pain as if a “blowtorch” was lit inside her. But Pitre, 30, who was born weighing only 2 pounds, 2 ounces, has begun forging a path to...
Wilson’s disease is a rare disorder of copper metabolism, an “orphan disease” – a condition so uncommon that its diagnosis and treatment had been neglected. The disease was recognised by the British neurologist Kinnear Wilson in 1912, but a simple means of detecting it did not exist until the 1950s,...
New York, NY — The Hereditary Neuropathy Foundation (HNF) announced today the formation of a Research Consortium (HNF-RC) designed to speed the development of new therapies for Charcot-Marie-Tooth disease (CMT), which affects approximately 1 million US citizens, and is the most common inherited neuromuscular disorder worldwide. The HNF has made...
CHICAGO – Higher amounts of visceral abdominal fat in midlife are linked to the development of Alzheimer’s disease, according to research being presented next week at the annual meeting of the Radiological Society of North America (RSNA). Visceral fat is fat surrounding the internal organs deep in the belly. Researchers...
CAMBRIDGE, Mass. — Biogen Inc. (Nasdaq: BIIB) today announced the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion recommending by consensus the approval of the high dose regimen of nusinersen for the treatment of 5q spinal muscular atrophy (SMA). 5q SMA...
Vancouver, Canada. A new study from researchers at the University of British Columbia’s Faculty of Medicine reveals a direct link between high insulin levels, common among patients with obesity and Type 2 diabetes, and pancreatic cancer. The study, published in Cell Metabolism, provides the first detailed explanation of why people...