Cells that form cutaneous squamous cell carcinoma tumours prepare themselves to migrate to the lymph nodes to metastasise other organs, and they make changes so that they can survive this process. According to a study led by researchers from the Inflammatory and Neoplastic Dermatological Diseases Research Group at the Hospital del Mar Medical Research Institute, published in the journal Life Science Alliance, these cells stop consuming glucose so that they can survive by using LDL cholesterol molecules, the so-called bad cholesterol. This new marker may be a promising candidate for treatments involving lipid metabolism inhibitors targeting these cells to prevent metastasis.
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HOUSTON – Marker Therapeutics, Inc. (Nasdaq:MRKR), a clinical-stage immuno-oncology company specializing in the development of next-generation T cell-based immunotherapies for the treatment of hematological malignancies and solid tumor indications, today announced completion of the six-patient safety lead-in portion of the Company’s Phase 2 trial of MT-401, its lead MultiTAA-specific T cell product...
London — MarketsandMarkets is pleased to announce the 4th Annual Orphan Drugs and Rare Diseases Conference, which is set to take place on the 9th-10th of October 2023 in London, UK. After the resounding success of the third annual conference, we are excited to bring together industry experts, researchers, and...
Calgary, Alberta – Marvel Biosciences Corp., and its wholly owned subsidiary, Marvel Biotechnology Inc., today reported promising interim results from its study on MB-204, a new treatment for autism, conducted by the iBraiN Inserm Lab in Tours, France. The study demonstrated that a single oral dose of MB-204 can restore...
Boston, Mass. – A new study by investigators from Mass General Brigham demonstrated that a remote team focused on identifying, educating and prescribing therapy can improve guideline-directed-medical-therapy (GDMT) adherence in patients with type 2 diabetes and high cardiovascular and/or kidney risk. The research team observed that patients who received education...
Chandan Bariya of Sankariya village of Limkheda Taluka was brought to the clinic of Samir Brahmbhat after complaining of severe abdominal pain. Tests demonstrated that the girl was suffering from a rare disorder called Rapunzel syndrome, where an individual pulls one’s hair out and then eats it. This condition normally...
Columbus, Ohio – When Susan Powers went in for surgery to replace her hip in 2018, the last thing on her mind was cancer. But Powers’ pre-surgery blood work alarmed doctors enough that they recommended she see an oncologist immediately. Her daughter, Cheryl Spile, drove her to the hospital, where...
BEDMINSTER, N.J. — Matinas BioPharma (NYSE: MTNB), a clinical-stage biopharmaceutical company focused on delivering groundbreaking therapies using its lipid nanocrystal (LNC) platform delivery technology, announces alignment with the U.S. Food and Drug Administration (FDA) on the design of a single Phase 3 registration trial of MAT2203 in patients with invasive...
How can inflammatory responses be stimulated or inhibited? How do inflammasomes act as inflammatory switches at a molecular level? Prof. Dr. Matthias Geyer from the Institute of Structural Biology at University Hospital Bonn, the transdisciplinary research area “Life & Health” and the ImmunoSensation2 Cluster of Excellence at the University of...
Rochester, Minnesota – Mayo Clinic Comprehensive Cancer Center and Columbia University received a five-year, $10.6 million U54 center grant from the National Cancer Institute (NCI) to further study combining the molecular analysis of glioblastoma with MRI. Glioblastoma is a fast-growing and aggressive brain tumor that begins as a growth of cells in the brain or spinal cord. As...