Southampton, UK – Scientists have taken a major step towards developing a blood test that could identify millions of people who spread tuberculosis unknowingly. A breakthrough study has discovered a group of biological markers that are found in high levels among infectious patients. The researchers hope the findings will pave...
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Toronto, Canada – Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins — a new but largely unrealized approach to the treatment of disease. The researchers developed a method to interrogate the...
Tokyo, Japan – The onset of psychosis can be predicted before it occurs, using a machine-learning tool which can classify MRI brain scans into those who are healthy and those at risk of a psychotic episode. An international consortium including researchers from the University of Tokyo, used the classifier to...
BUFFALO, N.Y. — A viral gene therapy developed by University at Buffalo researchers has reversed some brain abnormalities in infant mice with FOXG1 syndrome, a significant step toward one day treating children with this severe neurodevelopmental disorder. This mediated delivery of the FOXG1 gene via adeno-associated virus 9 (AAV9) is...
BUFFALO, N.Y. — More than a decade ago, physicians around the world began reporting cases due to a new hypervirulent strain of Klebsiella pneumoniae, which could infect and severely sicken otherwise healthy people. Thomas A. Russo, MD, at the University at Buffalo and the VA Western New York Healthcare System...
London, UK – Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice co-led by a UCL and Moorfields researcher. The international study observed that in eyes with sight loss caused by a particular genetic...
London, UK – Treatment of transthyretin-mediated amyloid cardiomyopathy (ATTR-CM) with acoramidis may significantly improve the 4-step primary hierarchical outcome containing components of mortality, morbidity, and function, with similar safety as placebo, according to an article published in The New England Journal of Medicine. “Acoramidis is a high-affinity TTR stabilizer that acts...
Bern, Switzerland – Researchers have developed a new method for triggering and imaging seizures in epilepsy patients, offering physicians the ability to collect real-time data to tailor epilepsy surgery. In contrast to previous practice, where physicians from neurology and nuclear medicine had to wait for hours to days in hopes...
Amsterdam, Netherlands – Water determines life: humans are three-quarters water. An international research team led by the University of Amsterdam (UvA) has now discovered how water also determines the structure of the material that holds us together: collagen. In a paper recently published in PNAS, the researchers elucidate the role...
Tucson, Arizona – A recent breakthrough study from the lab of Tanya Kalin, MD, PhD, professor of Child Health and Internal Medicine at the University of Arizona College of Medicine – Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung cancers. “We have identified the novel protein FOXF1 that...