Salt Lake City, Utah – Scientists at Huntsman Cancer Institute at the University of Utah (the U), the National Cancer Institute-designated cancer center for the Mountain West, have made a significant breakthrough in predicting the prognosis of triple-negative breast cancer (TNBC), a particularly aggressive disease. Their research, published in JCO...
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Salt Lake City, Utah – For the first time researchers have identified patterns of risk for several different types of cancer in men with fertility problems and their families. The study, published today in Human Reproduction, one of the world’s leading reproductive medicine journals, found that families of men who...
York, UK – Scientists have developed a new, safe and effective way to infect volunteers with the parasite that causes leishmaniasis and measure the body’s immune response, bringing a vaccine for the neglected tropical disease a step closer. The breakthrough, by a team from the University of York and Hull...
Zurich, Switzerland – Acute myeloid leukemia (AML) is an aggressive form of blood cancer. It is caused by mutations in a large number of genes that are acquired in the course of a person’s life. One of these genes – the tumor suppressor gene TP53 – plays a key role....
Zurich, Switzerland – CRISPR-Cas systems, which consist of protein and RNA components, originally developed as a natural defense mechanism of bacteria to fend off intruding viruses. Over the last decade, re-engineering these so-called “gene scissors” has revolutionized genetic engineering in science and medicine. The tools can be programmed to find...
Chengdu, China – Dementia stands as one of the most significant global health challenges of the 21st century, with over 50 million individuals worldwide currently affected, a number projected to triple by 2050, reaching 152 million, due to global population aging. Alzheimer’s disease (AD) is the predominant cause of dementia,...
Jerusalem, Israel – Professor Asaf Hellman and his research team at the Hebrew University-Hadassah Medical School have unveiled new findings in the realm of methylation-directed regulatory networks. Their study sheds light on the mechanisms governing the activation and suppression of mutation-driven disease genes, particularly in cases like glioblastoma, offering insights...
Tokyo, Japan – Autism spectrum disorder (ASD) is a complex neuropsychiatric condition, marked by diverse cognitive and sensorimotor challenges, difficulties with social communication, and distinct behavioral patterns. While genetic factors are known to play a role, the intricate mechanisms driving this condition remain elusive. Moreover, a unified and comprehensive theoretical...
DURHAM, N.C. – Autoimmune diseases are mysterious. It wasn’t until the 1950s that scientists realized that the immune system could harm the organs of its own body. Even today, the fundamental causes and inner workings of most autoimmune diseases remain poorly understood, limiting the treatment options for many of these...
Treatment-free remission (TFR) is feasible after 2 or more years of frontline nilotinib treatment in patients with chronic myeloid leukemia in chronic phase (CML-CP), reported researchers in a study published in Leukemia. Advances in the treatment of CML have improved outcomes for those with the disease; however, long-term treatment with tyrosine...