Houston, Texas – Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer. Findings from the multicenter EXTEND trial, published today in the Journal of Clinical Oncology, were first presented at the 2024 American Society of Clinical...
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INDIANAPOLIS, Ind. — Adipo Therapeutics, a late-stage, preclinical biopharmaceutical company developing treatments for obesity and Type 2 diabetes, announced the successful completion of a $1.9 million bridge fund round. To date, Adipo has raised a total of $4 million in seed funding to advance the development of its lead asset...
Toyoake, Japan – Cervical cancer is a highly prevalent cancer, with approximately 500,000 new cases diagnosed each year. Shockingly, the number of individuals diagnosed with precursor lesions in the cervix—also known as cervical intraepithelial neoplasia (CIN)—is 20 times higher. As with many potentially malignant conditions, early diagnosis of cervical cancer...
New York, NY — Advancium Health Network, a public charity dedicated to advancing therapies for rare diseases, has awarded two major grants to accelerate research into a potential treatment for Autosomal Dominant Optic Atrophy (ADOA)—the most common hereditary optic neuropathy. Caused by mutations in the OPA1 gene, ADOA leads to...
Leipzig, Germany – “The aim of our multidisciplinary and broad-based project is to establish antimicrobial stewardship in sub-Saharan Africa and to prevent the transmission of infectious diseases through a One Health approach,” says Dr Ahmed Abd El Wahed. Research institutions from the seven countries involved in this network – Uganda,...
Salt Lake City, Utah – Some families call it a trial of faith. Others just call it a curse. The progressive neurological disease known as spinocerebellar ataxia 4 (SCA4) is a rare condition, but its effects on patients and their families can be severe. For most people, the first sign...
Baltimore, Maryland – Age-related changes that cause the skin to stiffen and become less elastic may also contribute to higher rates of metastatic skin cancer in older people, according to research by investigators from the Johns Hopkins Kimmel Cancer Center. The study, published March 12 in Nature Aging, shows that increased...
Cambridge, Mass. – Rare disease company Agios Pharmaceuticals reached the primary endpoint in a Phase III study for its drug pyrukynd (mitapivat) in adults with non-transfusion-dependent alpha- or beta-thalassemia, according to the company’s announcement on Wednesday The Phase III ENERGIZE study met the primary endpoint of hemoglobin response, defined as...
London, UK – A new paper in Biology Methods & Protocols, published by Oxford University Press, indicates that it may soon be possible for doctors to use artificial intelligence (AI) to detect and diagnose cancer in patients, allowing for earlier treatment. Cancer remains one of the most challenging human diseases,...
Changchun, China – Hepatocellular carcinoma (HCC) is the most common type of liver cancer. It is a major global health concern with rising rates, particularly in North Africa and East Asia. Although potentially curable in the early stages, HCC often remains undetected until it’s too late for effective treatment. This...