Researchers studying the bleeding disease hemophilia in mice have increased the rodents’ ability to produce a crucial blood-clotting protein, a new study says. Their success may pave the way for human trials. Past studies have successfully introduced a gene into animals’ cells to make the clotting protein, Factor VIII, which...
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Dunedin, New Zealand – People suffering from Long COVID or Myalgic Encephalomyelitis /Chronic Fatigue Syndrome (ME/CFS) could benefit from a coordinated treatment strategy, a new University of Otago study has found. The pilot study, published in Nature Portfolio’s Scientific Reports, an open-access journal, has confirmed what researchers have suspected for...
New York, NY – Structural insights into a potent antimalarial drug candidate’s interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute. The antimalarial molecule, TDI-8304, is one of a new class...
PHILADELPHIA – How molecules of the oldest branch of the human immune system have interconnected has remained a mystery. Now, two new structures, both involving a central component of an enzyme important to the complement system of the immune response, reveal how this system fights invading microbes while avoiding problems...
Munich, Germany – Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products from Bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools for synthetic biology. By exploring protein evolution, a team led by Helge Bode from...
London, UK – New findings reveal that the body undergoes significant, systematic changes across multiple organs during prolonged periods of fasting. The results demonstrate evidence of health benefits beyond weight loss, but also show that any potentially health-altering changes appear to occur only after three days without food. The study,...
Charlottesville, Virginia – About one-third of autistic people are unable to communicate using speech, and most are never provided an effective alternative. However, a new study from scientists at the University of Virginia suggests that many of these individuals are literate, raising the possibility that they could learn to express...
HOUSTON, TX ― Researchers at The University of Texas MD Anderson Cancer Center built a new atlas of lung cells, uncovering new cellular pathways and precursors in the development of lung adenocarcinoma, the most common type of lung cancer. These findings, published today in Nature, open the door for development...
Cincinnati, Ohio – An international, multisite phase 3 trial co-led by a University of Cincinnati researcher found Parkinson’s disease medication delivered through an infusion pump is safe and effective at reducing symptoms for longer periods of time. These results, published March 15 in the Lancet Neurology journal, could lead to...
Researchers show that patients with central diabetes insipidus who lack anti-rabphilin-3A antibodies could be at a higher risk of tumor development Toyoake Aichi, Japan – Central diabetes insipidus (CDI), a rare condition involving the destruction or degeneration of neurons of the hypothalamic-posterior pituitary in the brain, has several likely underlying...