Cambridge, UK – The microbiome can identify those who benefit from combination immunotherapy across multiple different cancers, including rare gynaecological cancers, biliary tract cancers and melanoma. Researchers from the Wellcome Sanger Institute, the Olivia Newton-John Cancer Research Institute in Australia, and collaborators, have identified specific strains of bacteria that are...
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In a breakthrough for the treatment of aggressive solid cancers, researchers at Children’s Hospital of Philadelphia (CHOP) have developed a novel cancer therapy that targets proteins inside cancer cells that are essential for tumor growth and survival but have been historically impossible to reach. Using the power of large data...
Statins are the most commonly used medication in lowering blood cholesterol, prescribed to tens of millions in the Western world. Statins act through inhibition of the enzyme HMG CoA reductase. Nearly 20% of statin users develop muscle symptoms (“statin myopathy”) including weakness and pain. In about 1%, this myopathy is...
CORAL GABLES, FL — Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) are the most important vector-borne viral diseases in the World. Around 50-100 million cases appear each year putting 2.5 billion people at risk of suffering this debilitating and sometimes fatal disease. Dengue Fever is prevalent in the Tropics....
New York, NY – Tisch Cancer Institute researchers discovered that a certain type of chemotherapy improves the immune system’s ability to fight off bladder cancer, particularly when combined with immunotherapy, according to a study published in Cell Reports Medicine in January. These findings may explain why the approach, cisplatin chemotherapy,...
Boston – Researchers from Boston University School of Medicine (BUSM) have quantified the probability of a male who carries a “high normal” variant of the Huntington’s Disease (HD) gene having a child who develops the disease. Although thought to be a very rare event, the probability has never been estimated...
Bloomington, Indiana – Researchers at Indiana University College of Arts and Sciences have identified a missing link that can help protect the brain from aging. Hui-Chen Lu, professor and director of the Linda and Jack Gill Center for Biomolecular Science at IU, alongside graduate students Sen Yang and Zhen Xian...
Barcelona, Spain – Researchers have discovered key mutations in certain cancer cells that make them resistant to WRN inhibitors, a new class of anti-cancer drugs. The yet-to-be-published findings are presented on Friday at the 36th EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain. Werner helicase (WRN)...
Philadelphia, PA – Advancements in the care of premature babies are leading to improved survival rates. However, the incidence of neonatal diseases with life-long consequences such as bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) is increasing. A novel study has implicated granulocyte colony-stimulating factor (G-CSF) in both BPD and...
DURHAM, N.C. – The brain’s neurons tend to get most of the scientific attention, but a set of cells around them called astrocytes – literally, star-shaped cells – are increasingly being viewed as crucial players in guiding a brain to become properly organized. Specifically, astrocytes, which form about half the...