LEXINGTON, Mass. and AMSTERDAM — uniQure N.V., a leading gene therapy company advancing transformative therapies for patients with severe medical needs, today announced updated interim data including up to 30 months of follow-up from 39 patients enrolled in the ongoing U.S. and European Phase I/II clinical trials of AMT-130 for...
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Nijmegen, The Netherlands – TB is a major threat to public health, being among the leading causes of death worldwide. In 2021, the disease claimed the lives of 1.6 million people, making it the second leading infectious killer after COVID-19.[1] Drug-resistant TB and long treatment regimens have increased the urgency...
Birmingham, England – Societal acceptance of autism varies considerably across different countries, with lowest levels of acceptance found in Japan and Belgium, new research shows. A survey of 306 autistic individuals from eight countries revealed that around three quarters of respondents do not feel accepted, or only sometimes feel accepted,...
Southampton, UK – Scientists have taken a major step towards developing a blood test that could identify millions of people who spread tuberculosis unknowingly. A breakthrough study has discovered a group of biological markers that are found in high levels among infectious patients. The researchers hope the findings will pave...
Toronto, Canada – Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins — a new but largely unrealized approach to the treatment of disease. The researchers developed a method to interrogate the...
Tokyo, Japan – The onset of psychosis can be predicted before it occurs, using a machine-learning tool which can classify MRI brain scans into those who are healthy and those at risk of a psychotic episode. An international consortium including researchers from the University of Tokyo, used the classifier to...
London, UK – Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice co-led by a UCL and Moorfields researcher. The international study observed that in eyes with sight loss caused by a particular genetic...
London, UK – Treatment of transthyretin-mediated amyloid cardiomyopathy (ATTR-CM) with acoramidis may significantly improve the 4-step primary hierarchical outcome containing components of mortality, morbidity, and function, with similar safety as placebo, according to an article published in The New England Journal of Medicine. “Acoramidis is a high-affinity TTR stabilizer that acts...
Bern, Switzerland – Researchers have developed a new method for triggering and imaging seizures in epilepsy patients, offering physicians the ability to collect real-time data to tailor epilepsy surgery. In contrast to previous practice, where physicians from neurology and nuclear medicine had to wait for hours to days in hopes...
Amsterdam, Netherlands – Water determines life: humans are three-quarters water. An international research team led by the University of Amsterdam (UvA) has now discovered how water also determines the structure of the material that holds us together: collagen. In a paper recently published in PNAS, the researchers elucidate the role...