PITTSBURGH, PA— The current standard of care for treating patients with stage 3 colorectal cancer is to use adjuvant therapy with FOLFOX, a combination of the drugs fluorouracil, leucovorin, and oxaliplatin. Although effective, the use of oxaliplatin can lead to known adverse events, mainly neurotoxicity that may be chronic. NRG...
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The NRG Oncology clinical trial NRG-LU002 comparing local consolidative therapy (LCT) and maintenance systemic therapy to maintenance systemic therapy alone for limited-metastatic non-small cell lung cancer (NSCLC) recently reached the trial’s accrual goal for the Phase 2 portion of the study. The trial is expected to remain closed for required...
PARAMUS, N.J. — NS Pharma, Inc., a subsidiary of Nippon Shinyaku Co., Ltd., announced that, on December 13, 2023, the European Commission (EC) has granted orphan drug designation for NS-089/NCNP-02, which is being developed for the treatment of Duchenne muscular dystrophy (Duchenne), a rare and deadly genetic disorder that occurs...
Singapore – A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is particularly relevant for patients undergoing colorectal cancer treatments. Reporting their finding in Cell, the researchers describe a new process...
SINGAPORE – Immunotherapy is a type of cancer treatment that uses the body’s own immune system to help fight cancer. This is by stimulating the immune response to recognise and attack cancer cells more effectively. The treatment involves using substances that boost the immune system, teaching immune cells to target...
Singapore – In a breakthrough for the advanced study of gut health, scientists from the National University of Singapore (NUS) have developed a 3D microscopic version of the human intestines condensed into a small chip about half the size of a five-cent coin. This new cell culturing platform, known as the...
Boston, Mass. — Tuberculosis (TB) is the leading infectious killer worldwide, with 10.6 million cases and 1.6 million deaths in 2021 alone. One in five incident TB cases were attributable to malnutrition, more than double the number attributed to HIV/AIDS. Like HIV/AIDS, malnutrition is a cause of secondary immunodeficiency, known...
Fort Lee, NJ — Nuvectis Pharma, Inc., a clinical-stage biopharmaceutical company focused on the development of innovative precision medicines for the treatment of serious conditions of unmet medical need in oncology, today announced a collaboration with Mayo Clinic to evaluate NXP800 in an Investigator-sponsored clinical trial in cholangiocarcinoma. Mitesh Borad,...
Abu Dhabi – A team of researchers at NYU Abu Dhabi, led by Professor Sehamuddin Galadari, has discovered that the tumor suppressor protein Prostate apoptosis response-4 (Par-4) can cause a unique type of cell death called ferroptosis in human glioblastoma – the most common and aggressive type of brain tumor...
New York, NY – A diet that limits meat and dairy but is rich in fruits, vegetables, grains, and nuts is linked to less erectile dysfunction, urinary incontinence, and other common side effects seen in prostate cancer patients, a new study shows. Led by researchers at NYU Grossman School of...