Vienna, Austria – Groundbreaking research presented today at UEG Week 2024 reveals a promising new treatment strategy for type 2 diabetes (T2D) that could significantly reduce or even eliminate the need for insulin therapy.1 This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with...
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WEST LAFAYETTE, Ind. — Purdue University researchers are developing and validating a patent-pending treatment for incurable glioblastoma brain tumors. Glioblastomas are almost always lethal with a median survival time of 14 months. Traditional methods used against other cancers, like chemotherapy and immunotherapy, are often ineffective on glioblastoma. Sandro Matosevic, associate...
Reston, VA—A new radiotheranostic system has the ability to detect and treat ovarian cancer noninvasively, according to new research published in the April issue of The Journal of Nuclear Medicine. Combining the highly specific huAR9.6 antibody with PET and therapeutic radionuclides, this theranostic platform may provide more personalized treatment to improve...
Rehovot, Israel – Researchers from Israel identified novel small molecules that can selectively lower the levels of mutant Huntington (Htt) mRNA and protein in Huntington disease (HD). These molecules reduced mitochondrial dysfunction, restored the expression of brain-derived neurotrophic factor (BDNF), improved motor function, and reduced anxious-like behavior in a mouse model...
Boston, Mass. — In the development of Parkinson’s disease (PD), the changes that will lead to neurodegeneration take place in the brain long before patients show any symptoms. But without a test that can detect these changes, it’s difficult to intervene early to more effectively slow disease progression. To address...
ROOT, Switzerland — NovoCure Ltd. (NASDAQ: NVCR) today announced that the final patient has been enrolled in the global phase 3 TRIDENT clinical trial evaluating the safety and efficacy of initiating Optune Gio® (formerly known as Optune®) concurrent with radiation therapy and temozolomide (TMZ) for the treatment of adult patients...
BOSTON, Mass. — Novotech, the global full-service clinical Contract Research Organization (CRO) that partners with biotech companies to accelerate the development of advanced and novel therapeutics at every phase, has released today an industry-leading report on Duchenne Muscular Dystrophy (DMD) Clinical Trial Landscape. The report includes emerging genetic therapies, funding...
PITTSBURGH, PA— The current standard of care for treating patients with stage 3 colorectal cancer is to use adjuvant therapy with FOLFOX, a combination of the drugs fluorouracil, leucovorin, and oxaliplatin. Although effective, the use of oxaliplatin can lead to known adverse events, mainly neurotoxicity that may be chronic. NRG...
The NRG Oncology clinical trial NRG-LU002 comparing local consolidative therapy (LCT) and maintenance systemic therapy to maintenance systemic therapy alone for limited-metastatic non-small cell lung cancer (NSCLC) recently reached the trial’s accrual goal for the Phase 2 portion of the study. The trial is expected to remain closed for required...
PARAMUS, N.J. — NS Pharma, Inc., a subsidiary of Nippon Shinyaku Co., Ltd., announced that, on December 13, 2023, the European Commission (EC) has granted orphan drug designation for NS-089/NCNP-02, which is being developed for the treatment of Duchenne muscular dystrophy (Duchenne), a rare and deadly genetic disorder that occurs...