Memphis, TN – Scientists from St. Jude Children’s Research Hospital, Seattle Children’s and the Children’s Oncology Group (COG) have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood cancer. The identification of genomic predictors of relapse...
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SAN FRANCISCO, Calif. — The question of what causes complex neurological diseases such as Alzheimer’s or multiple sclerosis continues to confound scientists and doctors, with the unknowns standing in the way of early diagnoses and effective treatments. Even among identical twins who share the same genetic risk factors, one may...
Blacksburg, Viginia – Tackling brain cancer is complicated, but groundbreaking new research could help add another tool to the cancer-fighting arsenal. A team from Georgia Tech and Virginia Tech published a paper in APL Bioengineering in May that explores a new option that could one day be used to target...
Ulsan, South Korea – A groundbreaking study conducted by Professor Jiyoung Park and her research team in the Department of Biological Sciences at UNIST has identified FAM3C, a metabolism-regulating signaling molecule produced by cancer-associated adipocytes (CAAs), as a key regulator of breast cancer progression within the tumor microenvironment (TME). The...
ARLINGTON HEIGHTS, Ill. — Two new practice parameters from the Joint Task Force for Practice Parameters (JTFPP) offer evidence-based recommendations for the diagnosis and management of anaphylaxis and atopic dermatitis (AD) in pediatric and adult patients. The Joint Task Force is a partnership between the American College of Allergy, Asthma...
Hunter researchers have helped to discover two more genes that have been linked to the development of multiple sclerosis (MS). The research, published in this week’s international scientific journal Nature Genetics, provides clues to the causes of MS. The discovery was made by the ANZgene consortium which is made up...
Washington, D.C. — Vaccines that prevent smallpox and mpox come in 2 varieties. One uses a single shot of a live virus but carries risk of serious side effects; the other, which is newer and made with replication deficient virus, has fewer side effects but requires 2 doses. An experimental...
New York, NY – Two new studies led by researchers at Hospital for Special Surgery (HSS) have uncovered key biological mechanisms driving systemic sclerosis (SSc), or scleroderma – a rare and often devastating autoimmune disease that causes fibrosis (tissue hardening) and inflammation. The research, published in the March issue of...
LA JOLLA, CA — Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn’s disease. This protein, known as SLC15A4, has been considered largely “undruggable,” as most researchers had longed struggled to isolate...
LOS ANGELES, Calif. – For the last three decades, breakthroughs have been sparse for soft tissue sarcomas, which are rare cancers that affect muscles, fat and other connective tissues. Today, a global team of researchers funded by a Stand Up To Cancer® (SU2C) grant announced clinical trial results that point...