Zamzam Sheriff Phillips syndrome


Zamzam Sheriff Phillips syndrome is a rare genetically congenital syndrome. It is associated with the symptoms of Aniridia, ectopia lentis, abnormal upper incisors and mental retardation. It is believed to be inherited in an autosomal recessive fashion. Not a lot of research has been undertaken of this particular disease so thus far there is no known gene that affects this condition. However it has been hypothesised that the symptoms described are found at a particular gene, though mental retardation is believed to be due to a different genetic cause. Consanguinuity has been attributed to affect the chances of inheriting this disease.


  • Absence of iris
  • Aniridia
  • Mental retardation
  • Difficulty concentrating
  • Learning difficulties
  • Facial abnormalities
  • Facial deformities
  • Teeth deformities
  • Visual problems
  • Acuity difficulties


The condition is believed to be genetically inherited, which is attributed to consanguinuity as affecting the chances of its inheritance. Although there is a hypothesis that symptoms are found in a particular gene, the gene that affects the condition is not yet known. However, a different genetic cause is believed to have caused mental retardation.


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