Senior-Loken syndrome 4


A rare inherited disorder characterized by kidney dysfunction and progressive eye disease. Type 4 is caused by a chromosomal defect on chromosome 1p36.


* Thirst * Excessive urination * Progressive vision loss * Blindness * Arterial hypertension * Tubulointerstitial nephropathy * Anemia * Increased blood urea nitrogen * Increased blood creatinine level * Thickening of kidney filtration tissues * End stage kidney disease * Polyuria * Enuresis * Inability to concentrate urine * Kidney failure * Metabolic acidosis * Growth retardation * Renal salt wasting * Retinitis pigmentosa


The signs and symptom information on this page attempts to provide a list of some possible signs and symptoms of Senior-Loken syndrome 4. This medical information about signs and symptoms for Senior-Loken syndrome 4 has been gathered from various sources, may not be fully accurate, and may not be the full list of Senior-Loken syndrome 4 signs or Senior-Loken syndrome 4 symptoms. Furthermore, signs and symptoms of Senior-Loken syndrome 4 may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Senior-Loken syndrome 4 symptoms.


Prognosis of Senior-Loken syndrome 4: poor with death occurring before adulthood