Renal cysts and diabetes syndrome


The 'renal cysts and diabetes syndrome' is an autsmal dminant disrder cmprising (1) nndiabetic renal disease resulting frm abnrmal renal develpment, and (2) diabetes, which in sme cases ccurs earlier than age 25 years and is thus cnsistent with a diagnsis f maturity-nset diabetes f the yung (MDY). The renal disease is highly variable and includes renal cysts, glmerular tufts, aberrant nephrgenesis, primitive tubules, irregular cllecting systems, ligmeganephrnia, enlarged renal pelves, abnrmal calyces, small kidney, single kidney, hrseshe kidney, and hyperuricemic nephrpathy. Affected individuals may alshave abnrmalities f the genital tract,