A rare condition where an inherited deficiency of properdin (a blood plasma component) affects immunity. In particular, susceptibility to meningococcal disease is increased. There are three subtypes of the disorder: type I is a total deficiency, type II is a partial deficiency and type III is a deficiency due to abnormal function of the properdin.
Increased susceptibility to meningococcal disease
signs and symptoms of Properdin deficiency may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Properdin deficiency symptoms.