Properdin deficiency- X-linked
Overview
A rare condition where an inherited deficiency of properdin (a blood plasma component) affects immunity. In particular, susceptibility to Neisseria infections is increased.
Symptoms
* Fulminate meningociccemia * Meningococcal meningitis * Systemic lupus erythematosus * Discoid lupus
Causes
Alcoholism (acute) Aortic insufficiency Febrile disorder Thyrotoxicosis
Diagnosis
After you detect a bounding pulse, check the patient’s other vital signs, and then auscultate the heart and lungs for abnormal sounds, rates, or rhythms. Ask the patient if he has noticed weakness, fatigue, shortness of breath, or other health changes. Review his medical history for hyperthyroidism, anemia, or a cardiovascular disorder, and ask about his use of alcohol.