Prolactinoma- familial


A pituitary tumor that secretes prolactin and occurs in a familial pattern of inheritance. The tumor is benign but can cause symptoms due to high prolactin levels or compression of the optic nerve.


* Increased blood prolactin level * Menstrual changes * Headache * Impaired vision * Abnormal milk secretion * Infertility * Impaired male sexual function * Reduced libido * Vaginal dryness * Erectile dysfunction * Reduced estrogen production in females * Reduced testosterone production in males


Familial prolactinoma is a distinct entity which is probably due to a genetic mutation promoting lactotroph proliferation.