Macular degeneration, polymorphic: An inherited vision disorder which affects both eyes.
Impaired vision Abnormal color vision Progressive vision loss
Age-related macular degeneration results from the formation of drusen (clumps of epithelium) or subretinal neovascular membrane in the macular region. It may be hereditary. Cigarette smoking and lack of antioxidants, such as vitamins C and E, may also enhance occurrence. Underlying pathologic changes occur primarily at the level of the retinal pigment epithelium, Bruch’s membrane, and choriocapillaris in the macular region. Drusen (bumps), which are common in elderly people, appear as yellow deposits beneath the pigment epithelium and may be prominent in the macula.
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