A very rare syndrome characterized by abnormal development of the kidneys which results in early kidney failure.
* Low birth weight * Kidney failure * Abnormal urine concentration * Urinary acidosis * High urine sodium level
* Developmental arrest of the metanephric blastema at 14-20 weeks' gestation causes oligomeganephronia. * Although oligomeganephronia is associated with some genetic syndromes, most cases of oligomeganephronia are sporadic. However, mutations in the paired-box transcription factor, (PAX2) have been seen even in persons with nonsyndromic oligomeganephronia. Recently, mutations in the homeobox transcription factor (hepatocyte nuclear factor-1 b) have been described in association with oligomeganephronia. Interestingly, the heterozygous mutation may be associated with development of the kidney lesion. * Vascular abnormalities and accidents have been associated with this type of renal hypoplasia. The cause of most oligomeganephronia cases is unknown.
Home medical testing related to Oligomeganephronic renal hypoplasia: * Bladder & Urinary Health: Home Testing: o Home Bladder Tests o Home Urinary Tract Infection (UTI) Tests o Home Cystitis Tests o Home Kidney Tests o Home Urine Protein Tests (Kidney Function) o Home Prostate Cancer Tests * Kidney Health: Home Testing: o Home Microalbumin Tests (Kidney) o Home Urine Protein Tests (Kidney) o Home Urinary Tract Infection (UTI) Tests
* Urinary & Bladder Specialists (Urology): o Urology o Urological Surgery * Kidney Health Specialists (Nephrology): o Nephrology (Kidney Health) o Pediatric Nephrology (Child Kidney Health) o Urology (Urinary/Bladder)