Oguchi disease
Overview
Oguchi disease is an autosomal recessive form of congenital stationary night blindness associated with fundus discoloration and abnormally slow dark adaptation.
Symptoms
* Discolored fundus - yellow or gray * Slow dark adaptation * Night blindness * Mitzuo's phenomenon
Causes
Several mutations have been implicated in the pathogenesis of Oguchi disease. These include mutations in the arrestin gene or the rhodopsin kinase gene. The condition is more frequent in individuals of Japanese ethnicity