Oculocerebrorenal syndrome
Overview
Oculocerebrorenal syndrome (also called Lowe syndrome) is a X-linked recessive disorder characterized by hydrophthalmia, cataracts, intellectual disabilities, aminoaciduria, reduced renal ammonia production and vitamin D-resistant rickets.
Symptoms
* Mental retardation * Hypotonia * Hyperactivity * Choreoathetoid movements * Screaming
Diagnosis
, Lumbosacral muscle strain –Most common etiology of low back pain –Most common cause of disability in adults
Prognosis
The 'prognosis' of Lowe oculocerebrorenal syndrome usually refers to the likely outcome of Lowe oculocerebrorenal syndrome. The prognosis of Lowe oculocerebrorenal syndrome may include the duration of Lowe oculocerebrorenal syndrome, chances of complications of Lowe oculocerebrorenal syndrome, probable outcomes, prospects for recovery, recovery period for Lowe oculocerebrorenal syndrome, survival rates, death rates, and other outcome possibilities in the overall prognosis of Lowe oculocerebrorenal syndrome. Naturally, such forecast issues are by their nature unpredictable.
Treatment
* In absence of red flag symptoms, return to activity as soon as possible; rest has not been shown to improve recovery * Acetaminophen, NSAIDs, opioids, and/or muscle relaxants for pain; epidural corticosteroid injections may be indicated for resistant pain * Patient education (weight loss, exercise, proper back biomechanics and ergonomics) * Physical therapy, including pain relief modalities (ice, heat, ultrasound), stretching, strengthening, aerobic conditioning, and relaxation therapy * Surgery may be indicated for refractory disease, large neurologic deficits, unbearable pain, or significant limitations