May-Hegglin anomaly


May-Hegglin Anomaly: An inherited blood disorder involving abnormalities in some of the blood components (platelets and certain leukocytes).


* Asymptomatic * Minor hemorrhages * Mild leukopenia * Mild reduction in level of blood platelets * Skin hemorrhage * Nosebleed * Excessive oral bleeding during dental procedures * Headache * Muscle weakness on one side of body * Intracranial bleeding


* Malignant hypertension * Thrombotic thrombocytopenic purpura * Schulman-Upshaw syndrome


Prognosis of May-Hegglin Anomaly: good.The 'prognosis' of May-Hegglin Anomaly usually refers to the likely outcome of May-Hegglin Anomaly. The prognosis of May-Hegglin Anomaly may include the duration of May-Hegglin Anomaly, chances of complications of May-Hegglin Anomaly, probable outcomes, prospects for recovery, recovery period for May-Hegglin Anomaly, survival rates, death rates, and other outcome possibilities in the overall prognosis of May-Hegglin Anomaly. Naturally, such forecast issues are by their nature unpredictab


* Dependent upon etiology, severity, and presence of acute bleeding * ITP –Bone marrow exam before treatment with steroids –Treatment with IVIG or WinRho does not need bone marrow exam –Platelet transfusion is ineffective in ITP but should be considered at counts 10,000 –Treatment does not hasten resolution of ITP –About 90% of children have resolution in 3–6 months –Older girls more likely to become chronic * Acute, isolated thrombocytopenia is almost never malignancy –Marrow exam should be done in children with chronic or complex illness or with no response to therapy