Limb-girdle muscular dystrophy- type 2D


An autosomal recessive form of limb-girdle muscular dystrophy where muscle weakness and atrophy is caused by mutations of the alpha-sarcoglycan gene. The severity of the condition is greatly variable from wheelchair confinement at the age of 9 years to asymptomatic adults. Most tend to live to their third decade. More detailed information about the symptoms, causes, and treatments of Limb-girdle muscular dystrophy type 2D is available below.


Shoulder girdle muscle weakness Shoulder girdle muscle wasting Scapular muscle weakness Scapular muscle wasting Lordosis Foot drop Loss of mobility


Leg disorders Hip disorders Knee disorders Brain disorders Balance disorders - see causes of balance disorders Inner ear infection Vitamin B12 deficiency Vision disorders


Prognosis for Limb-girdle muscular dystrophy type 2D: severe cases are confined to wheelchair by 13 years whereas as milder cases are capable of walking even after 16 years of age