A rare syndrome characterized by the development of a number of benign skin tumors that develops from smooth muscle tissue. In familial cases, the condition occurs in several members of a family. Tumors may also occur in other parts of the body.
* Small skin nodule * Painful skin nodule
Treatment of cutaneous leiomyomas is based on symptomatic or cosmetic concerns and is usually limited to excision of single lesions. Asymptomatic lesions are left untreated especially when multiple lesions are present, because of the likelihood of recurrence. Symptomatic lesions that are not amenable to resection are more difficult to treat. The etiology of pain in leiomyomas is unclear, but it is thought to be related to smooth-muscle contraction or compression of nerve bundles in larger tumors . Therapeutic interventions include oral nitroglycerin, nifedipine, and phenoxybenzamine, which is aimed at relaxing smooth muscle, and topical analgesics for pain.