Amaurosis congenita of Leber, type 3
Leber congenital amaurosis type 3
Leber congenital amaurosis 3 (LCA3) is a rare inherited retinal disease (retinal dystrophy) that starts during the fetal stage. Vision impairment is obvious at birth or within months of birth. Type 3 is distinguished from the other forms of this condition by the genetic origin of the defect - chromosome 14q23.3, RDH12 gene.
- Retinal dysfunction
- Sensitivity to light
- Impaired vision
- Slow pupil response
Prognosis of Leber congenital amaurosis 3 is blindness by early adulthood.