Kyrle disease
Overview
Kyrle disease: A skin disorder often associated with diabetes mellitus or kidney failure.
Symptoms
The list of signs and symptoms mentioned in various sources for Kyrle disease includes the 7 symptoms listed below:
- Papular eruptions
- Hyperkeratotic cone-shaped papular plugs
- Hyperkeratotic verrucous plaques
- Diabetes mellitus
- Hepatic insufficiency
- Presence of albumin in the urine
- Excess sugar in the urine
Note that Kyrle disease symptoms usually refers to various symptoms known to a patient, but the phrase Kyrle disease signs may refer to those signs only noticable by a doctor.
Causes
Other Possible Causes of these Symptoms
- Diabetes mellitus
Diagnosis
In cases of diffuse thickening of the skin, a thyroid profile with T 3 , T 4 , and TSH should be done. This should also identify hypothyroidism. A positive ANA test with a speckled pattern will help identify scleroderma, but a skin biopsy should also be done. An antisclerodermal antibody titer is also useful if available. Esophageal motility studies will be helpful in early diagnosis. A skin biopsy will help identify many of the other conditions mentioned above. Urine for porphyrins will help identify porphyria.