Kleiner Holmes syndrome


At a glance: Malformative syndrome characterized by the association of polysyndactyly and hallux valgus. Synomym: Hallux varus and Preaxial Polysysndactyly. Incidence and genetic inheritance: One case report of two siblings. Exact incidence unknown.Autosomal recessive inheritance. Clinical aspects: In 1980, Kleiner and Holmes described two brothers with bilateral hallux varus, One brother had duplication-triplication of the great toes and the other bad unusually broad great toes with Incomplete duplication of the phalanges. The parents were not related and showed no skeletal abnormality. Anesthetic considerations: No specific anesthetic considerations.