Hay Wells syndrome recessive type


A rare recessively inherited genetic disorder characterized by ankyloblepharon, ectodermal dysplasia, and cleft lip and/or cleft palate. The recessive form of this condition is distinguished by the presence at birth of adhesions between the upper and lower jaws.


  • Cleft palate
  • Ankyloblepharon
  • Adhesions between upper and lower jaws
  • Cleft lip
  • Conical teeth
  • Widely spaced teeth
  • Missing permanent teeth
  • Palmar keratoderma
  • Plantar keratoderma
  • Peeling skin at birth
  • Erythematous skin at birth
  • Eroded skin at birth
  • Thickened skin
  • Partial, patchy absence of sweat glands
  • Partial inability to sweat
  • Increased skin pigmentation
  • Absent nails
  • Dystrophic nails
  • Wiry hair
  • Sparse hair
  • Alopecia
  • Oval face
  • Broad nasal bridge
  • Maxillary hypoplasia