Factor XII deficiency
Overview
Factor XII deficiency is an inherited disorder with no symptoms. Factor XII is a protein involved in blood clotting. A deficiency of this factor does not cause abnormal bleeding in the affected person, but the blood takes longer than normal to clot in a test tube.
Symptoms
There are usually no symptoms.
Causes
Factor XII deficiency is a rare hereditary disorder. It is usually found when clotting tests are done for routine screening. It is not associated with abnormal bleeding.
Prevention
This is an inherited disorder. There is no known way to prevent it.
Diagnosis
* Abnormal factor XII assay * Prolonged partial thromboplastin time
Prognosis
The outcome is expected to be good without treatment.
Treatment
Treatment is generally unnecessary.
Resources
This condition is usually discovered by the health care provider, when prolonged clotting is noticed in the process of running other laboratory tests.