A very rare syndrome involving the early start of symptoms of dystonia and parkinsonism. The onset of the symptoms usually occurs suddenly over weeks or even hours and then progresses slowly.
Synonims: Rapid-onset dystonia-parkinsonism, DYT 12, RDB.
• Muscle cramping
• Muscle spasms
• Unsteady walk
• Involuntary limb movements
• Speech problems
Dystonia is a late sign of this disorder, which is marked by slowly progressive dementia. The patient typically displays decreased attention span, amnesia, agitation, an inability to carry out activities of daily living, dysarthria, and emotional lability.
* Bradykinesia: A medical term used to describe slow execution of movements and the ability to adjust the body's position is reduced. * Drooling: Excessive saliva in the mouth. * Dysarthria: Imperfect articulation of speech * Dysphagia: When swallowing is difficult * Dystonia: Muscle problems causing movement disorders * Guam disease: A nerve degeneration disorder that occurs particularly in Guam and involves progressive dementia and parkinsonism which ultimately leads to death. * Limping: Walking with a limp or other gait problem * Muscle cramps: A condition which is characterized by the uncontrolled contractions of muscles * Muscle spasms: Involuntary movement or contraction of muscles without full control * Speech symptoms: Problems with speech or voice.