Congenital generalized fibromatosis


A rare disorder where a number of noncancerous tumors form just about any part of the body.


* Multiple fibroblastic skin tumors * Multiple fibroblastic muscle tumors * Multiple fibroblastic bone tumors * Multiple fibroblastic visceral tumors


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In many cases, the tumors are present at birth (congenital), develop within the first few weeks of life, or may initially become apparent before the age of two years. Following initial growth and multiplication (proliferation) of tumor cells, the tumors usually eventually recede and disappear on their own (spontaneously). Those with solitary or multiple lesions without visceral involvement typically have a benign disease course. However, in infants with severe or widespread involvement of vital internal organs (i.e., multicentric, visceral involvement), potentially life-threatening complications may occur.