Charcot-Marie-Tooth disease- Type 2B1


Charcot-Marie-Tooth disease, Type 2B1: CMT is an inherited neurological disease characterized by the gradual degeneration of nerves which starts in the hands and feet and results in progressive numbness, muscle weakness and loss of function. Type 2B1 has an autosomal dominant inheritance and involves a defect in the LMNA gene located on chromosome 1


* Weak muscles in lower limbs * Wasted muscles in lower limbs * Loss of reflexes in lower limbs * High foot arch