Biemond syndrome type 2: A rare inherited condition characterized by mental retardation, obesity, polydactyly and underdeveloped genitals.
* Pituitary dwarfism * Mental retardation * Iris coloboma * Obesity * Secondary hypogenitalism
Obesity results from excessive calorie intake and inadequate expenditure of energy. Theories to explain this condition include hypothalamic dysfunction of hunger and satiety centers, genetic predisposition, abnormal absorption of nutrients, and impaired action of GI and growth hormones and of hormonal regulators such as insulin. An inverse relationship between socioeconomic status and the prevalence of obesity has been documented, especially in women. Obesity in parents increases the probability of obesity in children, from genetic or environmental factors, such as activity levels and learned patterns of eating. Psychological factors, such as stress or emotional eating, may also contribute to obesity. Rates of obesity are climbing, and the percentage of children and adolescents who are obese has doubled in the last 20 years.