Ankyloglossia heterochromia clasped thumbs
Overview
An extremely rare inherited condition characterized by clasped thumbs (adducted thumb), different colored eyes and a tongue anomaly where the tongue has limited mobility due to the fact that it is excessively attached to the floor of the mouth.
Symptoms
- Different colored eyes
- Clasped thumbs
- Tongue-tied
- Limited tongue mobility
- Feeding problems
Causes
- 18-Hydroxylase deficiency - poor feeding
- 2-methylbutyryl-coenzyme A dehydrogenase deficiency - poor feeding
- 3 alpha methylcrotonyl-Coa carboxylase 1 deficiency - feeding difficulties
- 3 alpha methylcrotonyl-coa carboxylase 2 deficiency - feeding difficulties
- 3-methylcrotonyl-CoA carboxylase deficiency - feeding difficulties