Amyopathic dermatomyositis

Synonyms

1

Overview

Amyopathic dermatomyositis (ADM) is a form of dermatomyositis characterized by the presence of typical skin findings without muscle weakness. Some of the skin changes that suggest dermatomyositis include a pink rash on the face, neck, forearms and upper chest; Gottron's papules and heliotrope eyelids. Pruritis and photosensitivity are common, as is scalp inflammation and thinning of the hair. While patients with amyopathic dermatomyositis should not have clinically evident muscle weakness, minor muscle abnormalities may be included. Fatigue is reported in at least 50% of patients. Some cases have been associated with internal malignancy and/or interstitial lung disease.

Symptoms

  • Skin rash
  • Reddish-purple skin patches
  • Purple eyelids
  • Purple spots on bony joints
  • Photosensitivity
  • Abnormality of the eye
  • Autoimmunity
  • EMG abnormality
  • Muscle weakness
  • Myalgia
  • Periorbital edema

Causes

  • Hives
  • Eczema
  • Contact dermatitis
  • Food allergies
  • Egg allergy
  • Peanut allergy
  • Wheat allergy

Treatment

Treatment may include sun avoidance, ample use of sunscreen, topical corticosteroids, antimalarial agents, methotrexate, mycophenolate mofetil, or intravenous (IV) immunoglobulin.

Resources

  • NIH